What is Hydroxypinacolone Retinoate
Hydroxypinacolone retinoate (HPR) is formed by the dehydration condensation of retinoic acid and pinacol. Compared with the three retinoid brothers (alcohol, aldehyde, acid), it has higher stability and less irritation.
Basic information
| Name | Hydroxypinacolone Retinoate |
| Cas | 893412-73-2 |
| Molecular Formula | C26H38O3 |
| Appearance | Yellow crystal powder |
| Storage conditions | 1-10°C |
| Density | N/A |
| Molecular weight | 398.57800 |
Shipping
| ≤100kg | By express(door to door)DHL.FEDEX.TNT.EMS,etc. |
| Fast:3-5 day | |
| ≤100-1000kg | By air |
| Fast:5-7 day | |
| ≥1000kg | By sea (Tianjin port,Qingdao port.Shanghai port) |
| Slow:7-45 day |
Applications of Hydroxypinacolone Retinoate
It is a retinol derivative that has the function of regulating the metabolism of the epidermis and stratum corneum. It can resist aging, reduce seborrhea, dilute epidermal pigment, and prevent skin aging and prevention. Acne, whitening and lightening effects.
The effects of using pinacol modification are direct effect, small molecular weight, easier transdermal absorption, low irritation, and high stability. It can be said that it has obvious advantages over other types of retinoids.
HPR has a stronger effect at the gene transcription level than retinol, but at the transcription level Less effective than trans-retinoic acid. Compared with the untreated control, HPR significantly promoted the synthesis of procollagen. Histological examination showed that the highest dose of HPR had a stronger effect than trans-retinoic acid, but the induced inflammation was no greater than that of the latter. Stronger. Based on these results, it is believed that HPR is an alternative to retinoic acid for skin anti-aging, but has fewer skin side effects.
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